Heiko Witt Selected Research

chymotrypsin C

1/2022	Risk of chronic pancreatitis in carriers of loss-of-function CTRC variants: A meta-analysis.
7/2015	Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis.
2/2014	Functional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitis.
11/2013	Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk.
1/2008	Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.

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Heiko Witt Research Topics

Disease

36	Chronic Pancreatitis 09/2022 - 05/2002
25	Pancreatitis 03/2022 - 01/2003
9	Infections 01/2016 - 10/2004
5	Fibrosis (Cirrhosis) 01/2020 - 08/2007
5	Chronic Hepatitis C 01/2013 - 09/2008
4	Hereditary pancreatitis 02/2014 - 11/2003
3	Pain (Aches) 03/2018 - 12/2016
3	Inflammation (Inflammations) 02/2016 - 08/2007
3	Hepatitis C 01/2016 - 09/2009
3	Liver Diseases (Liver Disease) 01/2016 - 01/2008
3	Asthma (Bronchial Asthma) 09/2009 - 04/2004
3	Pancreatic Neoplasms (Pancreatic Cancer) 12/2006 - 01/2003
2	Diabetes Mellitus 01/2017 - 07/2003
2	Malnutrition (Nutritional Deficiencies) 01/2017 - 09/2008
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2014 - 01/2007
2	Abdominal Pain (Pain, Abdominal) 09/2013 - 09/2008
2	Atopic Dermatitis (Atopic Eczema) 09/2009 - 05/2009
2	Tropical Calcific Pancreatitis 01/2009 - 10/2002
1	Body Weight (Weight, Body) 01/2020
1	Pancreatic Pseudocyst 01/2017
1	Flatulence 12/2016
1	Lymphoma (Lymphomas) 02/2016
1	Hepatitis A (Hepatitis, Infectious) 01/2016
1	Diarrhea 12/2015
1	Atrophy 03/2015
1	Crohn Disease (Crohn's Disease) 10/2014
1	Colitis 04/2014
1	Ehlers-Danlos Syndrome (Syndrome, Ehlers-Danlos) 09/2013
1	Syphilis 09/2013
1	Steatorrhea 05/2013
1	Virus Diseases (Viral Diseases) 01/2013
1	Alcoholic Liver Cirrhosis (Alcoholic Cirrhosis) 01/2012

Drug/Important Bio-Agent (IBA)

14	TrypsinogenIBA 01/2022 - 05/2002
11	Kazal Pancreatic Trypsin InhibitorIBA 04/2013 - 05/2002
8	EnzymesIBA 09/2022 - 01/2008
5	Lipase (Acid Lipase)FDA Link 03/2022 - 09/2013
5	chymotrypsin CIBA 01/2022 - 01/2008
5	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 01/2008
5	TrypsinIBA 01/2019 - 06/2006
4	DNA (Deoxyribonucleic Acid)IBA 03/2022 - 05/2009
4	Trypsin InhibitorsIBA 01/2009 - 10/2002
3	Transcription Factors (Transcription Factor)IBA 02/2016 - 05/2009
2	Proteins (Proteins, Gene)FDA Link 03/2022 - 10/2005
2	Calcium-Sensing ReceptorsIBA 10/2021 - 10/2020
2	CalciumIBA 10/2020 - 01/2020
2	CeruletideIBA 01/2020 - 02/2016
2	Carboxypeptidases A (Carboxypeptidase A)IBA 10/2015 - 10/2013
2	NucleotidesIBA 04/2014 - 09/2009
2	CytokinesIBA 04/2014 - 04/2007
2	InterferonsIBA 01/2013 - 09/2009
1	Pancreatic Elastase (Elastase)IBA 09/2022
1	Chymotrypsin FDA Link 09/2022
1	Phospholipases A2 (Phospholipase A2)IBA 03/2022
1	EstersIBA 03/2022
1	Transient Receptor Potential ChannelsIBA 12/2021
1	ChymotrypsinogenIBA 12/2020
1	InflammasomesIBA 10/2020
1	Prednisone (Sone)FDA LinkGeneric 01/2020
1	Calcium Channels (Calcium Channel)IBA 01/2020
1	GlucocorticoidsIBA 01/2020
1	Lactoylglutathione LyaseIBA 01/2019
1	Protein Isoforms (Isoforms)IBA 10/2018
1	erucylphosphocholineIBA 03/2018
1	WP 1IBA 01/2017
1	FructoseIBA 12/2016
1	Toll-Like Receptors (Toll-Like Receptor)IBA 02/2016
1	Phosphotransferases (Kinase)IBA 02/2016
1	Taurocholic Acid (Sodium Taurocholate)IBA 02/2016
1	Lipoproteins (Lipoprotein)IBA 01/2016
1	oxidized low density lipoproteinIBA 01/2016
1	ApolipoproteinsIBA 01/2016
1	Apolipoprotein E4IBA 01/2016
1	Apolipoproteins E (ApoE)IBA 01/2016
1	LigandsIBA 01/2016
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2016
1	Protons (Proton)IBA 12/2015
1	SodiumIBA 12/2015
1	CarboxypeptidasesIBA 10/2015
1	Protease Inhibitors (Protease Inhibitor)IBA 05/2015
1	Palm OilIBA 03/2015
1	Fatty Acids (Saturated Fatty Acids)IBA 03/2015
1	Autophagy-Related ProteinsIBA 03/2015
1	AntioxidantsIBA 03/2015
1	myosin IXBIBA 10/2014
1	Sulfonic AcidsIBA 04/2014
1	Dextran SulfateIBA 04/2014
1	Pattern Recognition ReceptorsIBA 04/2014
1	sym-trinitrobenzeneIBA 04/2014
1	Peptides (Polypeptides)IBA 04/2014
1	Acetylmuramyl-Alanyl-IsoglutamineIBA 04/2014
1	Amylases FDA Link 09/2013
1	AutoantibodiesIBA 09/2013
1	PancreatinIBA 05/2013
1	Interferon LambdaIBA 01/2013
1	chymotrypsinogen CIBA 01/2013
1	Heme (Haem)IBA 01/2012
1	Heme Oxygenase-1IBA 01/2012

Therapy/Procedure

6	Therapeutics 03/2018 - 03/2007
2	Liver Transplantation 06/2009 - 01/2008
1	Intraperitoneal Injections 02/2016